DAMS Mercury Fact Sheet #7

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Endocrine Effects of Mercury from Amalgam

  1. Mercury has been documented to be an endocrine disrupting chemical that selectively accumulates in the hormone glands and has significant adverse effects at very low levels of exposure.
  2. Studies find that millions have chronic mercury exposure more than the U.S. government’s health guideline for mercury. The largest exposures of both inorganic and methyl mercury to most adults were found to be from amalgam dental fillings, since bacteria and yeast methylate inorganic mercury to methyl mercury. Those with several amalgams typically have mercury exposures 10 times the average of those without amalgam, and after amalgam replacement, the mercury excretion level declines by 90%.
  3. Children with amalgam have mercury levels in urine at least 4 times that of the average of those without amalgam and much higher ratios for saliva and feces. Mother’s amalgams are the largest fetal and neonatal exposure for most infants. The largest exposures to most young children were found to be from mercury thimerosal in vaccines.
  4. Studies found that many infants are receiving high levels of fetal and neonatal exposure to mercury sufficient to cause developmental effects that damage the metals detoxification system to the extent that continued exposure to toxic metals such as mercury thimerosal, lead, and arsenic results in accumulation of toxic levels of these metals. This is commonly leading to neurological conditions such as autism, Asperger’s Syndrome, Attention Deficient Hyperactive Disorder(ADHD) if not properly treated.
  5. Recent National Academy of Sciences reports and other studies have found that approximately 50% of U.S. pregnancies now result in spontaneous abortions, birth defects, neurological conditions, or chronic developmental disorders. Studies document that the majority of these are due to toxic exposures, and most children are receiving dangerous levels of toxic exposures.
  6. Chronic mercury exposure has been documented to be commonly causing widespread endocrine system effects including hypothyroidism, autoimmune thyroiditis, impaired conversion of thyroid and other hormones, pituitary hormone deficiencies, and adrenal hormone imbalances.
  7. Some of the endocrine related conditions/symptoms found to be commonly caused by these hormonal effects in infants and children include widespread neuropsychiatric conditions and developmental disorders such as autism, ADHD, dyslexia, learning disabilities, mood disorders, mental retardation, spontaneous abortions, eczema, asthma, systemic allergies, behavioral problems, and juvenile delinquency.
  8. Some of the endocrine related conditions/symptoms found to be commonly caused by mercury in adults include hypothyroidism, chills, chronic fatigue, fibromyalgia, depression and mood disorders, anxiety, anger, memory loss, balance problems, infertility, endometriitis, menstrual disorders, low sperm counts and diabetes.
  9. Mercury is extremely neurotoxic and immunotoxic, so that some of the conditions described are the collective result of neurotoxic, immunotoxic, and hormonal effects. These interactions have also been documented. Other toxic metals and chemicals, including dioxins, PCBs, organochlorine and organophosphate pesticides have neurotoxic, immunotoxic, and hormonal effects that act synergistically to cause these conditions. According to the research and thousands of clinical findings, mercury appears to be the most common significant toxic exposure, with the most clearly documented adverse effects.


Documentation of this information is available from DAMS at amalgam.org.

DAMS is currently working with thousands of people in the U.S. dealing with serious health effects caused by exposure to mercury from amalgam and urges everyone to find out more about this major problem and to get involved in resolving these health safety issues. DAMS can provide information and help to anyone who is interested or who thinks they might have health problems related to their amalgam fillings.

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